Andrew Lo gives an insightful talk on the use of quantitative modeling of economics and how thats influenced the field. There are quite a few interesting topics in his talk, including the history of how a quantitative framework for economics came about, its assumptions and limitations, clarifying the difference between risk and uncertainty, and developing better heuristics to control/manage the non-quantitative parameters of economic behavior, using checklists, etc.
Video & more information: http://mitworld.mit.edu/video/794/
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